By grenade do we mean as in having an internal fuse. Presumably a wood plug with a hole in it filled with compressed meal designed to burn for a measured amount of time before exploding . Or an incendiary device as in Molotov cocktail. Having an external burning element, like a piece of tarry rope designed to set fire to the contents after the grenade shattered on impact . Quoting from a 1639 Tower of London inventory.
Powder Pots of earth.
Earthen bottels to be made in a round fashion ... half full of serpentine powder or somewhat more, there is also to be mixt with a quantity of Hoggs grease, Oyle of stone , Brimstone, saltpetre twice refined. Aqua vitae, pitch...
Sounds like the latter to me.
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